What Is It?
A 5-amino-acid peptide — the smallest GH-releaser ever made functional. Developed by Novo Nordisk in the late 1990s and described as "the first selective growth hormone secretagogue."
How Does It Work?
Older GH peptides like GHRP-2 and GHRP-6 are shotguns. They release GH — but also cortisol, prolactin, and hunger signals. Ipamorelin is a sniper. One target. Growth hormone. Nothing else gets touched. Stacks with CJC-1295 because they target different mechanisms in the same cell — CJC-1295 amplifies the speaker, Ipamorelin presses play.
Primary Benefits (research suggests)
- Selective for GH only (no cortisol, prolactin, or hunger spikes)
- Produces stronger GH pulse when stacked with CJC-1295 than either alone
- Smallest functional GH-releasing peptide ever made
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- Has one Phase 2 trial for postoperative ileus (not anti-aging) that didn't hit endpoints.
- Zero FDA approval.
- Long-term safety in healthy humans is unstudied.
- For research purposes only.
Research Sources
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